Design of a novel cell-permeable chimeric peptide to promote wound healing

A Small Peptide with Potential Ability to Promote Wound Healing

Wound-healing represents a major health burden, such as diabetes-induced skin ulcers and burning. Many works are being tried to find ideal clinical wound-healing biomaterials. Especially, small molecules with low cost and function to promote production of endogenous wound healing agents (i.e. transforming growth factor beta, TGF-β) are excellent candidates. In this study, a small peptide (tiger...

The potential of honey to promote wound healing in periodontology: a pilot randomized clinical trial

 Abstract Background & Objectives: Honey has been used as a nutraceutical in many traditional and ancient remedies. Considering well documented benefits of honey to accelerate wound healing, for the first time we aimed to assess intra oral surgical wound healing process with honey. Methods: We designed a pilot randomized placebo controlled cross-over clinical trial. Patients who required bilate...

A novel autologous cell-based therapy to promote diabetic wound healing.

OBJECTIVES We have previously shown that stromal cell-derived factor-1α (SDF-1α) is downregulated within diabetic cutaneous wounds, and that direct application of recombinant SDF-1α increases wound closure rates, neovascularization, and endothelial progenitor cell (EPC) recruitment. However, increased wound levels of exogenous SDF-1α results in elevated systemic levels of this proangiogenic che...

Estimating caloric needs to promote wound healing.

Green tea extract formulation may promote wound healing

Wound repair is a natural reaction to injury, which results in restoration of tissue integrity. In this study the healing effect of green tea extract formulation was investigated on open skin wound of rabbit. Active ingredients were extracted from green tea using water and glycerin (4:1) vehicle. Three cream formulations containing 2, 5 and 10% of green tea extract were prepared in the base. A ...